So, on to the good stuff.
I knew when I measured the top before loading that there were going to be issues. The panel itself wasn't square. This isn't unusual. They often are not, and the piecer might not even realize this, just trimming the panel according to the edges that are given. And then with 6 borders, the quilt has the potential to get even more out of alignment, as borders can easily stretch and if they're not measured properly can make things even more off. This panel was 1 1/2" off in width from top to bottom. On a wall hanging this would be noticeable and should be fixed if at all possible. It started with the panel being off, and the blue border also seemed to be an offender.